Te Ātete ki te Rifampicin i te Mycobacterium Tuberculosis
Ingoa hua
Kete Kimi Ātete Rifampicin HWTS-RT074A-Mycobacterium Tuberculosis (PCR Fluorescence)
Te mate urutā
Kua whānuitia te whakamahinga o te Rifampicin hei rongoā i ngā tūroro mate kohi pūkahukahu mai i te mutunga o te tekau tau atu i 1970, ā, he nui te pānga. Koinei te whiringa tuatahi hei whakapoto i te chemotherapy mō ngā tūroro mate kohi pūkahukahu. Ko te ātete ki te Rifampicin te take nui o te whakarerekētanga o te ira rpoB. Ahakoa kei te puta tonu mai ngā rongoā hou hei ārai i te kohi, ā, kei te piki haere tonu te whai huatanga haumanu o ngā tūroro mate kohi pūkahukahu, kei te iti tonu ngā rongoā hei ārai i te kohi, ā, he teitei te whakamahinga rongoā koretake i roto i ngā rongoā haumanu. He mārama, kāore e taea te whakamate katoa i te Mycobacterium tuberculosis i roto i ngā tūroro mate kohi pūkahukahu i te wā tika, ā, ka mutu, ka rerekē te ātete rongoā i roto i te tinana o te tūroro, ka roa ake te haere o te mate, ā, ka nui ake te tūponotanga o te mate o te tūroro. He pai tēnei kete mō te tātaritanga āwhina o te mate Mycobacterium tuberculosis me te kimi i te ira ātete rifampicin, he mea āwhina ki te mārama ki te ātete rongoā o te mycobacterium tuberculosis i pangia e ngā tūroro, me te whakarato i ngā huarahi āwhina mō te aratohu rongoā haumanu.
Te mate urutā
| Ingoa Whāinga | Kaituhituhi | Kaiwhakaiti | ||
| Pūtāhui TauhohengaA | Pūtāhui TauhohengaB | Pūtāhui TauhohengaC | ||
| rpoB 507-514 | rpoB 513-520 | IS6110 | FAM | Kāore |
| rpoB 520-527 | rpoB 527-533 | / | CY5 | Kāore |
| / | / | Mana whakahaere ā-roto | HEX(VIC) | Kāore |
Ngā Tawhā Hangarau
| Rokiroki | ≤-18℃ I te pōuri |
| Te roa o te oranga | 9 marama |
| Momo Tauira | Huware |
| CV | <5% |
| LoD | momo mohoao ātete-rifampicin: 2x103huakita/mL ira whakarerekētanga takatāpui: 2x103huakita/mL |
| Te motuhaketanga | Ka kitea e ia te mycobacterium tuberculosis momo-mohoao me ngā wāhi whakarerekētanga o ētahi atu ira ātete rongoā pērā i te katG 315G>C\A, InhA-15C>T, kāore ngā hua whakamātautau e whakaatu ana i te ātete ki te rifampicin, ko te tikanga kāore he tauhohenga whakawhiti. |
| Ngā Taputapu e Pā Ana: | Ngā Pūnaha PCR Wā-Tūturu SLAN-96P (Hongshi Medical Technology Co., Ltd.) |
Rere Mahi
