E ai ki te pūrongo hou mō te mate pukupuku o te ao, ko te mate pukupuku pūkahukahu tonu te tino take o ngā mate e pā ana ki te mate pukupuku puta noa i te ao, e 18.7% o aua mate katoa i te tau 2022. Ko te nuinga o ēnei kēhi he Mate Pukupuku Pūkahukahu Ehara i te Pūtau Iti (NSCLC). Ahakoa he iti noa ngā painga o te whakawhirinaki ki te rongoā matū mō te mate kua pāngia, kua nekehia te tauira.
Nā te kitenga o ngā tohu koiora matua, pērā i te EGFR, ALK, me te ROS1, kua tino hurihia te maimoatanga, mai i te huarahi kotahi-rahi-e-mō-te-katoa ki tētahi rautaki tika e aro ana ki ngā āhuatanga ira ahurei o te mate pukupuku o ia tūroro.
Heoi, ko te angitu o ēnei maimoatanga hou e whakawhirinaki katoa ana ki te whakamātautau ira tika me te pono hei tautuhi i te ūnga tika mō te tūroro tika.
Ngā Tohu Koiora Tino Hira: EGFR, ALK, ROS1, me KRAS
E whā ngā tohu koiora e tū ana hei pou mō te tātaritanga ngota o te NSCLC, hei ārahi i ngā whakataunga maimoatanga tuatahi:
-EGFR:Ko te whakarerekētanga ira tino kitea, inā koa i roto i ngā taupori Āhia, wāhine, me te hunga kāore e momi hikareti. Kua tino pai ake ngā putanga o ngā tūroro nā ngā aukati EGFR tyrosine kinase (TKI) pērā i te Osimertinib.
-ALK:Ko te "whakarerekētanga taimana," e kitea ana i roto i te 5-8% o ngā take NSCLC. He maha ngā wā ka tino aro atu ngā tūroro e hono ana ki te ALK ki ngā aukati ALK, ā, ka roa te ora.
-ROS1:He rite te hanganga o tēnei "taonga onge" ki te ALK, ā, 1-2% o ngā tūroro NSCLC te kitea. E wātea ana ngā maimoatanga whai hua, ā, he mea nui kia kitea.
-KRAS:I ngā wā o mua, i whakaarohia he "kore e taea te rongoā", he mea noa ngā whakarerekētanga KRAS. Nā te whakaaetanga tata nei o ngā aukati KRAS G12C kua hurihia tēnei tohu koiora mai i te tohu matapae ki tētahi whāinga mahi, ā, kua hurihia te tiaki mō tēnei rōpū tūroro.
Te Putea MMT: I Hangaia mō te Whakapono ki te Tātaritanga
Hei whakatutuki i te hiahia nui mō te tautuhi i ngā tohu koiora tika, ka tukuna e MMT he kohinga o ngā tohu CE-IVD wā-tūturuNgā kete kimi PCR, ia mea i hangaia ki te hangarau hou hei whakarite i te maia ki te tātaritanga.
1. Kete Kimi Huringa EGFR
-Hangarau ARMS Whakarei Ake:Ka whakanui ake ngā whakarei ake motuhake i te whakanui ake i te ira e pā ana ki ngā whakarerekētanga ira.
-Whakarei ake i te whākōkī:Ka nakunaku e ngā endonuclease here te papamuri ira momo-tūroa, ka whakarei ake i ngā raupapa ira whakarerekē me te whakarei ake i te taumira.
-Te Ārai i te Mahana:Ka whakaitihia te whakapūmautanga kore-motuhake e tētahi taahiraa wera motuhake, ka whakaitihia anō hoki te papamuri momo-mohoao.
-Ngā Painga Matua:Te aro nui kāore i te ōrite ki raro ki1%te auau o ngā ira whakarerekētanga, te tino tika me ngā mana whakahaere ā-roto me te whākōkī UNG, me te wā hurihanga tere o te tata ki120 meneti.
- Hototahi kingā tauira koiora kiko me ngā tauira koiora wai.
- Kete Kimi Hononga MMT EML4-ALK
- Teitei o te Tairongo:Ka kitea tika ngā whakarerekētanga ira honohono me te iti o te rohenga kitenga o te 20 tārua/tauhohenga.
-Tino tika:Kei roto ngā paerewa ā-roto mō te whakahaere tukanga me te whākōkī UNG hei ārai i te parahanga e toe ana, kia kore ai e puta he hua pai me he hua kino.
-Māmā & Tere:He mahi ngāwari, kati-ngongo e oti ana i roto i te 120 meneti pea.
-Hototahitanga o ngā taputapu:Ka taea te urutau ki ngā momo noangā taputapu PCR wā-tūturu, e tuku ana i te ngāwari mō ngā whakaritenga taiwhanga katoa.
- Kete Kimi Whakakotahitanga MMT ROS1
Teitei o te Tairongo:E whakaatu ana i te mahi tino pai mā te kite pono i te iti rawa o te 20 tārua/tauhohenga o ngā ūnga hanumi.
Tino tika:Mā te whakamahinga o ngā mana whakahaere kounga ā-roto me te whākōkī UNG ka whakarite kia pono te putanga o ia hua, ka whakaitihia te mōrearea o ngā hapa pūrongo.
Māmā & Tere:Hei pūnaha ngongo kati, kāore e hiahiatia he mahi uaua i muri i te whakanui. Ka puta ngā hua whai kiko, pono hoki i roto i te 120 meneti pea.
Hototahitanga o ngā taputapu:I hangaia kia whānui te hototahitanga ki ngā momo mīhini PCR matua, kia māmā ai te whakauru ki ngā rerengamahi taiwhanga o nāianei.
- Kete Kimi Hurihanga MMT KRAS
- Hangarau ARMS whakarei ake, mā te Whakarei i te Whākōkī me te Ārai i te Mahana.
- Whakarei ake i te whākōkī:Ka whakamahi i ngā endonuclease here hei nakunaku i te papamuri ira momo-tūroa, ā, ka whakarei ake i ngā raupapa ira whakarerekē me te tino whakarei ake i te taumira kitea.
-Te Ārai i te Mahana:Ka whakauru i tētahi taahiraa pāmahana motuhake hei whakaoho i te rerekētanga i waenga i ngā paraime motuhake ki ngā ira whakarerekētanga me ngā tauira momo-tūroa, ka whakaiti ake i te papamuri me te whakapai ake i te motuhaketanga.
- Teitei o te Tairongo:Ka tutuki i te tairongo kitea o te 1% mō ngā ira whakarerekētanga, kia mōhiotia ai te tautuhi i ngā whakarerekētanga iti-rahi.
-Tino tika:Ka tiakina e ngā paerewa ā-roto kua whakauruhia me te whākōkī UNG mai i ngā hua hē pai me ngā hua kino.
-Paewhiri Whānui:He whirihoranga whai hua hei āwhina i te kimi i ngā whakarerekētanga KRAS e waru puta noa i ngā ngongo tauhohenga e rua.
- Māmā & Tere:Ka puta he hua pono, he hua pono hoki i roto i te 120 meneti pea.
- Hototahitanga o ngā taputapu:Ka urutau pai ki ngā momo taputapu PCR, ka whakarato i te whānui o te whakamahinga mō ngā taiwhanga haumanu.
He aha i whiriwhiri ai koe i te otinga MMT NSCLC?
Whānui: He huinga katoa mō ngā tohu koiora NSCLC tino nui e whā.
He Pai Ake te Hangarau: Mā ngā whakarei ake (Whakarei i te Whākōkī, Ārai i te Pāmahana) ka tino motuhake me te aro ki ngā wāhi e tino hira ana.
Tere me te Whai Hua: Mā te whakamahi i te tikanga kotahi, tae atu ki te 120 meneti, ka tere ake te wā e pau ai te maimoatanga.
Ngāwari, Wātea hoki: Hototahi ki te whānuitanga o ngā momo tauira me ngā taputapu PCR matua, e whakaiti ana i ngā arai whakatinanatanga.
Whakamutunga
I tēnei wā o te oncology tino tika, ko ngā tātaritanga ngota te kāpehu e ārahi ana i te whakaterenga rongoā. Mā ngā kete kitenga matatau a MMT ka taea e ngā tākuta te mahere māia i te whenua ira o te NSCLC o te tūroro, ka wetewete i te pūmanawa whakaora ora o ngā maimoatanga kua tohua.
Contact to learn more: marketing@mmtest.com
Wā tuku: Whiringa-ā-rangi-05-2025