Te Whakarerekē i te Kitenga C. diff: Te Whakatutuki i te Tātaritanga Ngota Aunoa Katoa, Tauira-ki-te-Whakautu

He aha ngā take o te mate C. Diff?

1. Ko te mate diff te take o tētahi huakita e mōhiotia ana ko Clostridioides difficile (C. difficile), e noho ana i roto i ngā whekau, ā, kāore he kino. Heoi, ina whakararuraruhia te taurite huakita o te puku, he maha ngā wā ka whakamahia he paturopi whānui.C. uauaka nui rawa te tipu me te whakaputa paitini, ka arahi atu ki te mate.

Kei roto i tēnei huakita ngā āhua toxigenic me ngā āhua kore-toxigenic, engari ko ngā momo toxigenic anake (ngā paitini A me B) ka puta te mate. Ka whakaoho rātou i te mumura mā te whakararuraru i ngā pūtau epithelial o te puku. Ko te paitini A he enterotoxin e kino ana i te arai o te puku, e whakanui ana i te urunga, me te kukume i ngā pūtau ārai mate e tuku ana i ngā cytokines mumura. Ko te paitini B, he cytotoxin kaha ake, ka aro ki te angaanga actin o ngā pūtau, ka arahi ki te porowhita o te pūtau, te wehenga, ā, i te mutunga ka mate te pūtau. I te taha o ēnei paitini, ka puta te kino o te kiko me te urupare ārai mate kaha, e puta mai ana ko te colitis, te korere, ā, i ngā wā kino, ko te colitis pseudomembranous—he mumura nui o te koroni.

Me pēhea te horapa o te C. Diff?

1. He tino ngāwari te horapa o te rerekētanga. Kei roto i ngā hōhipera, e kitea pinepine ana i ngā ICU, i ngā ringa o ngā kaimahi hōhipera, i ngā papa me ngā kakau o te hōhipera, i ngā inemahana hiko, me ētahi atu taputapu hauora…

Ngā Take Tūpono mō te Mate C. Diff

• Te noho hōhipera mō te wā roa;
• Te rongoā paturopi;
• Ngā kaihoko chemotherapy;
• Te pokanga tata nei (ringaringa puku,te arai puku, pokanga kōpuku);
• Kai mā te ihu me te puku;
• Te mate urutā o mua o C. diff;

Ngā tohu o te mate C. Diff

Ka tino whakararuraru te mate C. diff. He maha ngā tāngata e pāngia ana e te mate korere me te mamae o te puku. Ko ngā tohu tino kitea ko:korere, mamae puku, whakapairuaki, kore hiahia kai, kirika.

I te kaha haere o te mate C. diff, ka puta he momo C. diff uaua ake e mōhiotia ana kote mate puku, te mate puku pseudomembranous, tae atu ki te mate.

Te Tātaritanga o te Mate Pukupuku C. Diff

Ahurea Huakita: Tairongo engarihe roa te wā (2-5 rā), kāore e taea te wehewehengā momo paitini me ngā momo kore-paitini;

Ahurea Paitini:e tautuhi ana i ngā momo paitini e puta ai te mate engari he roa te wā (3-5 rā) ā, he iti ake te tairongo;

Te Kitenga GDH:tere (1-2 hāora) ā, he iti te utu, he tino tairongo engari kāore e taea te wehewehe i ngā momo paitini me ngā momo kore-paitini;

Whakamātautau Whakakore Paitini Pūtau (CCNA):Ka kitea te paitini A me te paitini B me te tino aro engari he roa te wā (2-3 rā), ā, me whai whare motuhake me ngā kaimahi whakangungua;

Paitini A/B ELISAHe whakamātautau māmā, he whakamātautau tere hoki (1-2 hāora) he iti ake te aro, ā, he maha ngā hua kino teka;

Ngā Whakamātautau Whakarei Waikawa Karihi (NAAT)Tere (1-3 hāora) ā, tino tairongo, motuhake hoki, e kitea ai ngā ira e hanga ana i ngā paitini;

Hei tāpiri, ko ngā whakamātautau whakaahua hei tirotiro i ngā whekau, pērā i teNgā matawai CTmeNgā hihi-X, ka taea hoki te whakamahi hei āwhina i te tautuhi i te C. diff me ngā raruraru o te C. diff, pērā i te mate puku.

Te rongoā mō te mate C. Diff

He maha ngā kōwhiringa maimoatanga e wātea ana mō te mate C. diff. Kei raro nei ngā kōwhiringa pai rawa atu:

• Ko ngā paturopi ā-waha pērā i te vancomycin, te metronidazole, te fidaxomicin rānei e whakamahia whānuitia ana, nā te mea ka taea e te rongoā te haere mā te pūnaha nakunaku ka tae ki te koroni kei reira ngā huakita C. diff e noho ana.
• Ka taea te whakamahi i te metronidazole i roto i ngā uaua hei rongoā mēnā he kino te mate C. diff.
• Kua whakaatuhia te whai huatanga o ngā whakawhitinga moroiti paru ki te rongoā i ngā mate C. diff maha me ngā mate C. diff kino kāore e pai ki ngā paturopi.
• Tērā pea e hiahiatia he pokanga mō ngā take tino kino.

Auahatanga dotinga tātaritanga mai i te MMT

Hei whakautu i te hiahia mō te kimi tere me te tika o te C. difficile, ka whakaurua e mātou tā mātou Kete Kimi Waikawa Nucleic mō te ira paitini Clostridium difficile A/B, e whakamana ana i ngā tohunga hauora ki te tautuhi wawe me te tika, me te tautoko i te whawhai ki ngā mate urutā i puta mai i te hōhipera.

• Teitei o te Tairongo: Ka kitea te iti rawa o200 CFU/mL,;
• Te Whāinga Tika: Ka tautuhi tika i te C. uauaira paitini A/B, te whakaiti i ngā hua hē;
• Te Kimi Tika i ngā Mate TukutukuKa whakamahi i te whakamātautau waikawa karihi hei tautuhi tika i ngā ira paitini, ka whakatū i te paerewa koura mō te tātaritanga.
• Hototahi katoa kingā taputapu PCR matua e aro ana ki ētahi atu taiwhanga;

Otinga Tauira-ki-te-Whakautu kei rungaWhakamātautau-Makro me te Moroiti'sAIO800Taiwhanga PCR Waea

Aunoatanga Tauira-ki-te-Whakautu – Utaina tika ngā ngongo tauira taketake (1.5–12 mL), ka kore e tāpirihia ā-ringa ngā paipa. Ka aunoa katoatia te tango, te whakanui, me te kimi, ka whakaiti i te wā mahi me ngā hapa tangata.

• Parenga Parahanga 11-Papa – Mā te rere o te hau, te pēhanga kino, te tātari HEPA, te whakahoromata UV, ngā tauhohenga hiri, me ētahi atu ārai whakauru ka tiakina ngā kaimahi, ka whakarite hoki i ngā hua pono i te wā whakamātautau tere-rahi.

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