PCT/IL-6 Whakakotahitia

Ko te PCT te tohu o te calcitonin, he glycoprotein i tito mai i te 116 waikawa amino.Ko te rahinga ngota ko te 12.8kd.Karekau he mahi homoni.I raro i nga tikanga whaiaroaro, ko te PCT te nuinga ka whakahiatotia, ka hunahia e nga pūtau C thyroid.I te wa o te mate huakita, macrophages me monocytes i roto i te ate, lymphocytes me nga pūtau endocrine i roto i te pūkahukahu me te kiko intestinal synthesize me te huna i te nui o te PCT i raro i te mahi o te endotoxin, tumor necrosis factor-α me te interleukin-6, e arahi ana ki te pikinga nui. i roto i nga taumata PCT serum.
Ko te Interleukin-6 he cytokine e whakaatuhia ana e te punaha aukati i roto i te wa tuatahi o te whara me te mate.Ka hangaia e te fibroblasts, te monocytes/macrophages, T lymphocytes, B lymphocytes, epithelial cell, keratinocytes, me nga momo pukupuku pukupuku.Ko te IL-6 e rua nga mekameka glycoprotein, ko tetahi he mekameka α me te taumaha ngota o te 80kd;Ko tetahi atu he mekameka β me te taumaha ngota o te 130kd[5].Mena ka whakaihiihihia te tinana o te tangata e te mumura, ka piki tere nga taumata IL-6, na te mea ka takawaenga i te urupare o te wahanga whakapeka o te ate me te whakatairanga i te hanga o nga pūmua wahanga whakapeka penei i te C-reactive protein (CRP) me te serum amyloid A (SAA). ).Na reira, ko te IL-6 te tohu tuatahi ki te piki ina puta te mumura.