Te takenga o te ira bcr-ABL
Ingoa Hua
HWTS-GE010A-Tangata BCR-ABL FucR-MutR-Mutation Kit (Florescence PCR)
HWTS-GE016A-DIDE-DRELLE-DRED BCR-ABL Fusion Ko te whakauru kete (Florescence PCR)
Manganga
Ko te mate kiri ma te mate kiriku (cml) he mate kino o te kohinga o te hematopoietic. Neke atu i te 95% o nga turoro cml e kawe ana i te chromosome Philadelphia (pH) i o raatau toto toto. Ko te pathogenesis nui o te CML e whai ake nei: Ko te ira BCR-ABL e hangaia ana i waenga i te ABL Proto-Oncogene (abelson Murine Liratcomene BCR) ira i runga i te ringa roa o te chromosome 22 (22Q11); Ko te pūmua Fusion i whakauruhia e tenei ira tangata (TK), ka whakahohehia i ona huarahi waitohu (penei i te res, PI3K, me te Jak / Stop Cell) hei whakatairanga i nga kohinga. Tuhinga o mua. Ko te BCR-ABL tetahi o nga tohu tātaritanga whakahirahira a CML. Ko te huringa hihiri o tana taumata tuhinga he tohu pono mo te whakawakanga a leukemia ka taea te whakamahi ki te matapae i te reanga o te leukemia i muri i te maimoatanga.
Takiwā rerenga
| Whānau | BCR-ABL Fusion Gusion |
| Vic / Hex | Te mana o roto |
Tohu hangarau
| Pākoro | Wai: ≤-18 ℃ i roto i te pouri |
| Te Haahi-Ora | Wai: 9 marama |
| Momo tauira | Tauira Maroke wheua |
| Koropū | 1000 kape / ml |
| Whakawhāititanga
| Kaore he raru e pa ana ki etahi atu o nga hua o te Tel-aml1, E2A-PBX1, MLL-AF4, AML1-ETO, me te PML-Rara |
| Nga taputapu e tika ana | Te tono Biosystems 7500 nga punaha PCR-tūturu Te tono Biosystems 7500 nga punaha PCR-tino-tino tere Pūnaha PCR-ReanSTudio® 5 tūturu Slan-96P Pūnaha PCR tūturu Pūnaha PCR Realcycler®480 Ko te Pūnaha Tango-Real PCR Ma-6000 Motuhake TheMal Thermal Thermal Biorad CFX96 Pūnaha Real-Time Biorad CFX Opus 96 Pūnaha Real-Time |
