Te Whakarerekētanga Ira Tangata TEL-AML1
Ingoa hua
Kete Kimi Huringa Ira HWTS-TM016 TEL-AML1 Tangata (PCR Whakapūtanga)
Te mate urutā
Ko te mate pukupuku lymphoblastic acute (ALL) te mate pukupuku tino noa i roto i te tamarikitanga. I ngā tau tata nei, kua rerekē te mate pukupuku acute (AL) mai i te momo MIC (morphology, immunology, cytogenetics) ki te momo MICM (tāpiritanga o te whakamātautau koiora ngota). I te tau 1994, i kitea ko te whakakotahitanga TEL i te tamarikitanga i puta mai i te nekehanga ira kore-matapōkere t(12;21)(p13;q22) i roto i te mate pukupuku lymphoblastic acute (ALL) o te whakapapa-B. Mai i te kitenga o te ira whakakotahitanga AML1, ko te ira whakakotahitanga TEL-AML1 te huarahi pai ki te aromatawai i te matapae o ngā tamariki e pangia ana e te mate pukupuku lymphoblastic acute.
Hongere
| FAM | Ira honohono TEL-AML1 |
| ROX | Mana Whakahaere ā-roto |
Ngā Tawhā Hangarau
| Rokiroki | ≤-18℃ |
| Te roa o te oranga | 9 marama |
| Momo Tauira | tauira hinu wheua |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000 Ngā Tārua/mL |
| Te motuhaketanga | Kāore he tauhohenga whakawhiti i waenga i ngā kete me ētahi atu ira hanumi pēnei i te BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, me ngā ira hanumi PML-RARa. |
| Ngā Taputapu e Pā Ana | Ngā Pūnaha Koiora Whakamahia 7500 Ngā Pūnaha PCR Wā-Tūturu Ngā Pūnaha PCR Tere-Wā-Tūturu o Applied Biosystems 7500 Ngā Pūnaha PCR Wā-Tūturu a QuantStudio®5 Ngā Pūnaha PCR Wā-Tūturu SLAN-96P Pūnaha PCR Wā-Tūturu LightCycler®480 Pūnaha Kitenga PCR Wā-Tūturu LineGene 9600 Plus MA-6000 Pūrere Huringa Wera Wā-Tūturu Pūnaha PCR Wā-Tūturu BioRad CFX96 Pūnaha PCR Wā-Tūturu BioRad CFX Opus 96 |
Rere Mahi
Kete Tango RNAprep Toto Parakore Katoa (DP433).
