● Te mate kohi Mycobacterium
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Te Waikawa me te Rifampicin (RIF), te Ātete (INH) o te Mycobacterium Tuberculosis
E whakamahia ana tēnei kete mō te kimi i te DNA Mycobacterium tuberculosis i roto i te huakita tangata, te ahurea totoka (LJ Medium) me te ahurea wai (MGIT Medium), te wai horoi pūkahukahu, me ngā whakarerekētanga i roto i te rohe codon waikawa amino 507-533 (81bp, rohe whakatau ātete rifampicin) o te ira rpoB o te Mycobacterium tuberculosis rifampicin resistance, me ngā whakarerekētanga i roto i ngā wāhi whakarerekētanga matua o te Mycobacterium tuberculosis isoniazid resistance. Ka āwhina i te tautuhi i te mate Mycobacterium tuberculosis, ā, ka kitea ngā ira ātete matua o te rifampicin me te isoniazid, e āwhina ana ki te mārama ki te ātete rongoā o te Mycobacterium tuberculosis i pangia e te tūroro.
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Te Huringa INH o te Mycobacterium Tuberculosis
He pai tēnei kete mō te kimi kounga o ngā wāhi whakarerekētanga matua i roto i ngā tauira huware tangata i kohia mai i ngā tūroro Tubercle bacillus pai e arahi ana ki te mycobacterium tuberculosis INH: Rohe whakatairanga InhA -15C>T, -8T>A, -8T>C; Rohe whakatairanga AhpC -12C>T, -6G>A; whakarerekētanga homozygous o te KatG 315 codon 315G>A, 315G>C.
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Te Ātete ki te Rifampicin i te Mycobacterium Tuberculosis
He pai tēnei kete mō te kimi i te ira whakarerekētanga homozygous i roto i te rohe codon waikawa amino 507-533 o te ira rpoB e puta ai te ātete ki te Mycobacterium tuberculosis rifampicin.
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Te Ātete ki te Waikawa Nukleika me te Rifampicin i te Mycobacterium Tuberculosis
He pai tēnei kete mō te kimi kounga o te DNA Mycobacterium tuberculosis i roto i ngā tauira huware tangata i roto i te vitro, tae atu ki te ira whakarerekētanga homozygous i roto i te rohe codon waikawa amino 507-533 o te ira rpoB e puta ai te ātete ki te Mycobacterium tuberculosis rifampicin.
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Te DNA o te Mycobacterium Tuberculosis
He pai mō te kimi kounga o te DNA Mycobacterium tuberculosis i roto i ngā tauira huware haumanu tangata, ā, he pai hoki mō te tautuhi āwhina i te mate Mycobacterium tuberculosis.
