Mycobacterium Tuberculosis Isoniazid Resistensi Mutation

Whakaahuatanga Poto:

He pai tenei kete mo te rapunga kounga o nga waahi rerekee matua i roto i nga tauira sputum tangata i kohia mai i nga turoro Tubercle bacillus pai e arai ana ki te mycobacterium tuberculosis isoniazid resistance: InhA rohe kaiwhakatairanga -15C>T, -8T>A, -8T>C;AhpC rohe kaiwhakatairanga -12C>T, -6G>A;te rerekee homozygous o KatG 315 codon 315G>A, 315G>C .


Taipitopito Hua

Tohu Hua

ingoa hua

HWTS-RT137 Mycobacterium Tuberculosis Isoniazid Resistance Mutation Detection Kit (Ana Rewa)

Epidemiology

Ko te Mycobacterium tuberculosis, ko te Tubercle bacillus (TB), ko te huakita pathogenic e puta ai te mate kohi.I tenei wa, ko nga raau taero anti-mate kohi tuatahi e whakamahia ana ko te isoniazid, rifampicin me te hexambutol, me era atu. Heoi, na te he o te whakamahi i nga raau taero anti-mate kohi me nga ahuatanga o te hanganga pakitara o te mycobacterium tuberculosis, ka whakawhanake te mycobacterium tuberculosis i te aukati i nga raau taero ki nga raau taero anti-tuberculosis, e kawe mai ana i nga wero nui ki te aukati me te maimoatanga o te mate kohi.

Hongere

FAM MP waikawa karihi
ROX

Mana o roto

Tawhā Hangarau

Rokiroki

≤-18 ℃

Papa-ora 12 marama
Momo Tauira huka
CV ≤5%
LoD He 2x103 huakita/mL te tepe rapunga mo te momo mohoao aatete huakita isoniazid, a ko te tepe kitenga mo nga huakita mutant he 2x103 huakita/mL.
Tauwhāiti a.Karekau he tauhohenga whiti i waenga i te ira tangata, etahi atu mate pukupuku nontuberculous me te pneumonia i kitea e tenei kete.b.Ko nga waahi rereke o etahi atu ira aukati tarukino i roto i te momo mohoao Mycobacterium tuberculosis, penei i te rohe e whakatau ana i te rohe o te ira rifampicin rpoB, i kitea, a ko nga hua whakamatautau karekau he parenga ki te isoniazid, e tohu ana kaore he tauhohenga ripeka.
Nga taputapu e tika ana SLAN-96P Pūnaha PCR Wā-tūturuBioRad CFX96 Pūnaha PCR Wā-tūturu

LightCycler480® Pūnaha PCR Wā-tūturu

Rere Mahi

Mena ka whakamahi i te Tohutono & Micro-Test General DNA/RNA Kit (HWTS-3019) (ka taea te whakamahi me te Macro & Micro-Test Automatic Nucleic Acid Extractor (HWTS-3006C, HWTS-3006B)) na Jiangsu Macro & Micro-Test Med-Tech Co., Ltd. mo te tangohanga, taapirihia te 200μL o te mana kino me te tauira sputum tukatuka kia whakamatauria i te raupapa, me te taapiri 10μL o te mana o roto wehe ki te mana kino, tauira sputum tukatuka ki te whakamatauria, me nga kaupae e whai ake nei me tino whakatutuki i runga i nga tohutohu tangohanga.Ko te rahinga tauira kua tangohia he 200μL, ā, ko te 100 te rōrahi hauhāμL.


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